The Science

The Science behind Every Scoop

We're obsessed with clinical dosing, ingredient transparency, and formulas that actually work. No proprietary blends. Every ingredient is chosen based on research.

Explore Ingredients

Clinically Dosed, No Compromises.

Every Nello formula is built around ingredients based on peer-reviewed clinical studies. No micro-dosing, no proprietary blends hiding behind label tricks.

We publish every ingredient and every dose on the label. Full transparency, always.

Third-Party Tested. Every Batch.

Every batch of every Nello product is independently tested for purity, potency, and banned substances before it ships. We use GMP-certified facilities based in the US for all products.

No shortcuts. No exceptions.

The Best Forms, Not the Cheapest.

We source patented, clinically studied forms of our star ingredients: KSM-66 Ashwagandha, SRI-81 Shatavari, GeniusPure Alpha-GPC, Maizinol. These cost more. They are clinically proven. That's the point.

Every supplier is vetted. Every certificate of analysis is verified.

"If it doesn't work, why take it? If it doesn't taste good, nobody will. We made emotional wellness transparent, clinically dosed, and actually enjoyable. No mystery blends. No fairy dusting. Just wellness you can feel."

— Connor Noe + Mason Porter, Nello Co-Founders

Quality Assurance

From Raw Material to Your Hands

Every batch goes through a rigorous multi-step testing pipeline before it ships. No exceptions.

1

GMP Manufacturing

All Nello supplements are made in FDA registered and inspected facilities that are cGMP certified to ensure quality and safety.

2

Raw Material Testing

Ingredients are quarantined and released only after they are verified to pass identity, purity, and potency expectations.

3

Production Testing

Every product undergoes checks for defects at specific time intervals during the manufacturing process to make sure it meets our standards.

4

Third-Party Testing

Before your product ships, it is tested and confirmed by third-party ISO-accredited laboratories. Meaning every Nello supplement that makes its way to your home complies with USP heavy metal limits, has been checked for microbial contaminants, and has the right amount of active ingredients.

🏭GMP Certified
🔍Third-Party Tested
🇺🇸Made in the USA
📋Full Label Transparency
🚫No Proprietary Blends

The Research

Backed by Real Science

KSM-66 Ashwagandha

Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study

33%

Improvement in stress scores*

An 8-week randomized, double-blind, placebo-controlled trial showed KSM-66 significantly reduced serum cortisol levels and perceived stress scores in adults with chronic stress.

Cureus, 2019 View Study →

Magnesium Glycinate

Effects of Magnesium Supplementation on Subjective Anxiety

Significant

Reduction in stress and anxiety markers across studies

A systematic review of 18 studies found that magnesium supplementation was associated with reduced subjective anxiety and stress markers, especially for those pre-disposed to high stress.

Nutrients, 2017 View Study →

Alpha GPC

Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men

2x

Greater improvement on a demanding focus test vs. placebo*

A randomized, double-blind, crossover trial found that 350 mg of GeniusPure® Alpha GPC significantly improved attention and focus as measured by the Stroop test, a demanding cognitive attention test.

Nutrients, 2024 View Study →

L-Theanine

The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review

Significant

Assistance in reduction of stress and anxiety in people exposed to stressful conditions

This meta-analysis and systematic review concluded that supplementation of 200-400 mg/day of L-THE may assist in the reduction of stress and anxiety in people exposed to stressful conditions.

Plant Foods Hum Nutr., 2020 View Study →

Shatavari

Effects of Shatavari (Asparagus racemosus) Root Extract on Sexual Wellness in Women

34%

Increase in sexual wellness scores over 8 weeks*

A randomized, double-blind, placebo-controlled trial found that SRI-81 Shatavari improved sexual wellness scores over 8 weeks.

Int J Womens Health, 2026 View Study →

Maizinol

UP165, A Standardized Corn Leaf Extract for Improving Sleep Quality and Mood State

35%

Improvement in quality of sleep over 4 weeks

Maizinol (Zea mays) was clinically studied to improve subjective sleep quality over 4 weeks compared to placebo.*

J Med Food, 2023 View Study →

Our Standard

What We Never Do

No Proprietary Blends

Every ingredient and every dose is printed on the label. We never hide behind a blend name to obscure what you're actually getting.

No Fluff

Each formula is meticulously crafted to choose ingredients based on the science, with clinically studied ingredients grounding every formula.

No Unnecessary Fillers

No microcrystalline cellulose, no magnesium stearate filler, no inactive bulking agents. All of our ingredients serve a purpose.

No Fake Promises

We only claim what the research supports. No miracle cures, no exaggerated marketing. Just transparent science.

This is the standard. Every product. Every batch. Every time.

The best ingredients, researched for decades.

Every ingredient rigorously tested and clinically validated for efficacy and purity.